… attributed to innate differences among individuals in their … Despite the scientific advances
made, personalized medicine … could affect the potential for drug interaction with paroxetine, a …

… in men and women [4]. Importantly, there are also significant differences between men and
women in … In contrast, women benefit more from opioids that interact with the κ-receptor, eg …

… of differences in pharmacokinetics and pharmacodynamics, clinically relevant adverse drug
reactions differ between men and women (… suggests that the biology of sex and the impact of …

… The functional differences between the sexes are also … to the interaction of sexgender and
related pharmacogenetics on drug … pharmacodynamics: interaction with biological differences …

… scientific community [9]. Regulatory agencies have historically paid insufficient attention to
differences between women and men in … in women and men and considers sex differences in …

… on the interaction between gender and pharmacogenetics in … Network for Drug Safety, and
additional scientific consortia are … The most striking difference between males and females is …

… , transfer between body compartments, biological transformation, and elimination. Many
physiological variations between men and women may account for pharmacokinetic variances, …

… , and environmental factors mutually interact in defining sex/gender differences, and at the
… may strongly differ between males and females. While sex refers to biological and genetic …

… a product of the gene environment interaction is also vital to our … Both the pharmacokinetic
and pharmacodynamic components of … Pharmacogenetics of tamoxifen bio transformation is …

… With the emergence and development of pharmacogenomics, it is possible to discover …
variations in drug metabolizing enzymes, drug transporters, and direct and indirect interactions …